Acanthosis nigricans and oral glucose tolerance in obese children.

نویسندگان

  • Andrew T Scott
  • Andrea M Metzig
  • Robertson K Hames
  • Sarah Jane Schwarzenberg
  • Donald R Dengel
  • George R Biltz
  • Aaron S Kelly
چکیده

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منابع مشابه

Acanthosis nigricans in obese Chinese children.

OBJECTIVES. To investigate the demographic characteristics and insulin resistance in local overweight/obese Chinese children with and without acanthosis nigricans, and the associations of acanthosis nigricans with insulin resistance and other cardiometabolic co-morbidities. DESIGN. Case series with cross-sectional analyses. SETTING. A regional hospital in Hong Kong. PATIENTS. Chinese children a...

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Comparison of Insulin resistance in obese women with and without Acanthosis Nigricans

Background and aim: Acanthosis nigricans (AN) is characterized by hyperpigmented velvety plaques of body folds and neck. Insulin can have a role in the pathogenesis of this disease and hyperinsulinemia as a consequence of insulin resistance may stimulate the formation of the characteristic plaques of AN. In this study insulin resistance was compared in obese women with and without AN.</sp...

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Risk factors of impaired glucose tolerance in obese children aged 12-15 years old

Methods A cross sectional study was performed in 12-15 years old obese children from 10 Junior High Schools in Jakarta. History of T2DM in the family was determined by anamnesis with the parent. Clinical sign of acanthosis nigricans (AN) was fixed by physical finding. The intensity of physical activity was measured using the activity criteria according to World Health Organization. The diagnosi...

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Predicting Metabolic Syndrome in Obese Children and Adolescents: Look, Measure and Ask

OBJECTIVE To verify in obese children whether or not the presence of (i) high waist-to-height ratio (WHtR), (ii) family history for type 2 diabetes (T2D) and (iii) acanthosis nigricans (AN), singularly or together, might predict the occurrence of metabolic syndrome or prediabetes. METHODS 1,080 Italian obese children (567 females) were enrolled. Blood pressure, fasting plasma glucose, insulin...

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Acanthosis nigricans: a flag for insulin resistance

Objectives: Acanthosis nigricans refers to the velvety, black hyperpigmentation seen in the flexures. It is a cutaneous marker for insulin resistance (IR), some metabolic disorders and rarely malignancy. When secondary to IR, it is asymptomatic, except for the hyperpigmentation. The neck is the most accessible and easiest to grade. Our aim was to identify the predictive value of the grades of a...

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عنوان ژورنال:
  • Clinical pediatrics

دوره 49 1  شماره 

صفحات  -

تاریخ انتشار 2010